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KMID : 0362720230610110706
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Journal of the Korean Dental Association
2023 Volume.61 No. 11 p.706 ~ p.712
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Root coverage achieved with a connective tissue graft overlaid onto allogeneic demineralized dentin matrix incorporated with rhBMP-2
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Kwak Han-Wool
Um In-Woong
Ku Jeong-Kui
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Abstract
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Autogenous demineralized dentin matrix (DDM) has been widely used in implant dentistry and highlighted as a potential carrier of recombinant human bone morphogenetic protein-2 (rhBMP-2). Allogeneic DDM (Allo-DDM) is comparable to autogenous DDM in safety and effectiveness. The various endogenous growth factors in dentin, including BMP, transforming growth factor, fibroblast growth factor, and insulin growth factor suggest that DDM incorporated with rhBMP-2 (DDM/ rhBMP-2) may exert a synergistic effect that promotes soft tissue healing through angiogenic activity, in addition to its osteoinductivity. This case report describes a successful outcome of root coverage where connective tissue graft (CTG) was overlaid onto Allo-DDM incorporated with rhBMP-2 (Allo-DDM/rhBMP-2).
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KEYWORD
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demineralized dentin matrix, connective tissue graft, fistula closure, dentistry, root coverage
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